Blar i forfatter "Holmøy, Trygve"

Viser treff 1-4 av 4

    • Bone Turnover and Metabolism in Patients with Early Multiple Sclerosis and Prevalent Bone Mass Deficit: A Population-Based Case-Control Study 

      Moen, Stine Marit; Celius, Elisabeth Gulowsen; Sandvik, Leiv; Brustad, Magritt; Nordsletten, Lars; Eriksen, Erik Fink; Holmøy, Trygve (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Low bone mass is prevalent in ambulatory multiple sclerosis (MS) patients even shortly after clinical onset. The mechanism is not known, but could involve shared etiological risk factors between MS and low bone mass such as hypovitaminosis D operating before disease onset, or increased bone loss after disease onset. The aim of this study was to explore the mechanism of the low bone mass in early-stage ...

    • CSF, Blood, and MRI Biomarkers in Skogholt’s Disease—A Rare Neurodegenerative Disease in a Norwegian Kindred 

      Aspli, Klaus Thanke; Aaseth, Jan; Holmøy, Trygve; Blennow, Kaj; Zetterberg, Henrik; Kirsebom, Bjørn-Eivind Seljelid; Fladby, Tormod; Selnes, Per (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-26)
      Skogholt’s disease is a rare neurological disorder that is only observed in a small Norwegian kindred. It typically manifests in adulthood with uncharacteristic neurological symptoms from both the peripheral and central nervous systems. The etiology of the observed cerebral white matter lesions and peripheral myelin pathology is unclear. Increased cerebrospinal fluid (CSF) concentrations of protein ...

    • High dose vitamin D supplementation does not affect biochemical bone markers in multiple sclerosis - a randomized controlled trial 

      Holmøy, Trygve; Lindstrøm, Jonas Christoffer; Eriksen, Erik Fink; Steffensen, Linn Hofsøy; Kampman, Margitta Theodora (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-04)
      Background: <br> People with multiple sclerosis have high risk of osteoporosis and fractures. A poor vitamin D status is a risk factor for MS, and vitamin D supplementation has been recommended both to prevent MS progression and to maintain bone health. <br> Methods: <br> We assessed the effect of 20,000 IU vitamin D3 weekly compared to placebo on biochemical markers of bone metabolism in 68 ...

    • Month of birth and risk of multiple sclerosis: confounding and adjustments 

      Torkildsen, Øivind Fredvik; Aarseth, Jan Harald; Benjaminsen, Espen; Celius, Elisabeth Gulowsen; Holmøy, Trygve; Kampman, Margitta Theodora; Løken-Amsrud, Kristin Ingeleiv; Midgard, Rune; Myhr, Kjell-Morten; Riise, Trond; Torkildsen, Nina Agnethe Grytten (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      A month of birth effect on multiple sclerosis (MS) risk has been reported from different countries. Recent critics have suggested that this finding is caused by confounding and that adequately adjusting for year and place of birth would markedly reduce this effect. All inhabitants in Norway are registered in the Norwegian Population Registry (Statistics Norway), making this an ideal area for performing ...